Saturdays return in a big way to the University of Louisville’s home football schedule this fall, with five Saturday games at home and two on the road. The Cards also will have a record eight football games in the friendly confines of Papa John’s Cardinal Stadium. The not-so-great news is that there are some Wednesdays and Fridays in the mix. Oh well, it’s football, can’t complain too much.
| Date | Opponent | Location |
| TBA | KENTUCKY | PJCS |
| Sat., Sept. 6 | TENNESSEE TECH | PJCS |
| Wed., Sept. 17 | KANSAS STATE | PJCS |
| Sat., Sept. 27 | CONNECTICUT | PJCS |
| Fri., Oct. 10 | at Memphis | Memphis |
| Sat., Oct. 18 | MIDDLE TENNESSEE | PJCS |
| Sat., Oct. 25 | SOUTH FLORIDA | PJCS |
| Sat., Nov. 1 | at Syracuse | Syracuse |
| Sat., Nov. 8 | at Pittsburgh | Pittsburgh |
| Fri., Nov. 14 | CINCINNATI | PJCS |
| Sat., Nov. 22 | WEST VIRGINIA | PJCS |
| Thurs., Dec. 4 | at Rutgers | Picastaway |